| OEFEN | 04/08/2022 | 19:00 | SPE B | VK Liedekerke B (P4) | 1 – 0 |
| BEKER | 07/08/2022 | 16:00 | KVC Terheide B (P4) | SPE B | 2 – 1 |
| OEFEN | 11/08/2022 | 20:30 | VC Groot Dilbeek B (P4) | SPE B | 8 – 1 |
| BEKER | 14/08/2022 | 16:00 | SPE B | Bodegem Kapelle United B (P3) | 1 – 0 |
| OEFEN | 18/08/2022 | 20:00 | SK Vlezenbeek (RES) | SPE B | 4 – 3 |
| BEKER | 21/08/2022 | 16:00 | KFC Rhodienne-De Hoek B (P3) | SPE B | 4 – 1 |
| BEKER | 28/08/2022 | 16:00 | SPE B | Europa 90 Kraainem FC B (P4) | 1 – 1 |
| COMP | 31/08/2022 | 19:00 | SPE B | KFC Avenir Lembeek B | 3 – 2 |
| 04/09/2022 | 15:00 | VC Groot Dilbeek B | SPE B | 9 – 0 |
| 07/09/2022 | 18:30 | SPE B | FC Dworp | 1 – 1 |
| 10/09/2022 | 17:00 | SPE B | V. Beersel Drogenbos B | 1 – 2 |
| 18/09/2022 | 15:00 | VK Borchtlombeek B | SPE B | 0 – 6 |
| 25/09/2021 | 15:00 | SPE B | Football Club Machelen | 2 – 3 |
| 01/10/2022 | 19:30 | FC Galmaarden B | SPE B | 8 – 0 |
| 09/10/2022 | 15:00 | SPE B | Leeuw Brucom B | 0 – 3 |
| 16/10/2022 | 15:00 | KV Zuun B | SPE B | 5 – 6 |
| 23/10/2022 | 15:00 | SPE B | SK Vlezenbeek | 0 – 5 |
| 29/10/2022 | 18:00 | KFC Lennik B | SPE B | 1 – 2 |
| 06/11/2022 | 14:30 | SPE B | KFC MZ Tollembeek | 0 – 5 |
| 12/11/2022 | 14:30 | FC Herne B | SPE B | 10 – 1 |
| 19/11/2022 | 14:00 | SPE B | KV Kester-Gooik B | 1 – 3 |
| 25/11/2022 | 20:00 | KHO Huizingen B | SPE B | 1 – 1 |
| 04/12/2021 | 14:30 | SPE B | FC Schepdaal B | … – … |
| 18/12/2021 | 15:00 | KV Kester-Gooik B | SPE B | … – … |
| 08/01/2023 | 14:30 | SPE B | KV Zuun B | … – … |
| 14/01/2023 | 19:00 | V. Beersel Drogenbos B | SPE B | … – … |
| 22/01/2023 | 14:30 | SPE B | KHO Huizingen B | … – … |
| 29/01/2023 | 14:30 | Football Club Machelen | SPE B | … – … |
| 05/02/2023 | 15:00 | SPE B | FC Galmaarden B | … – … |
| 11/02/2023 | 19:30 | KFC MZ Tollembeek | SPE B | … – … |
| 25/02/2023 | 20:15 | Leeuw Brucom B | SPE B | … – … |
| 04/03/2023 | 19:00 | FC Schepdaal B | SPE B | … – … |
| 12/03/2023 | 15:00 | SPE B | VK Borchtlombeek B | … – … |
| 19/03/2023 | 15:00 | SK Vlezenbeek | SPE B | … – … |
| 26/03/2023 | 15:00 | SPE B | FC Herne B | … – … |
| 02/04/2023 | 15:00 | FC Dworp | SPE B | … – … |
| 23/04/2023 | 15:00 | KFC Avenir Lembeek B | SPE B | … – … |
